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15 January 2015

Symptoms predicting low testosterone levels in young, middle-aged and elderly men

Symptoms predicting low testosterone levels in young, middle-aged and elderly men
This summary gives an overview of two research papers that discuss the link between testosterone (T) levels and how often symptoms of low T occur. One study looked at the relationship between T levels and symptom occurrence in 360 middle-aged and elderly men (aged 40-90 years), the other in 352 younger men (aged <40 years). All men filled out a questionnaire to assess their symptoms on the same day that their T levels were measured.

1 January 2015

Testosterone-boosting Medications and Cardiovascular Risk

Testosterone-boosting Medications and Cardiovascular Risk

- a systematic review and meta-analysis

Cardiovascular risk associated with testosterone-boosting medications: a systematic review and meta-analysis. Corona G, Maseroli E, Rastrelli G, et al. Expert opinion on drug safety. Oct 2014;13(10):1327-1351.

Accumulating evidence shows beneficial effects of testosterone therapy on a wide range of health outcomes, including inflammation, insulin sensitivity, muscle mass, body fat mass, lipid profiles, endothelial (blood vessel) function, bone mineral density, energy and vitality, mood, sexual function and overall quality of life. Despite this, concerns have been raised that testosterone therapy could have detrimental effects on cardiovascular disease.

This editorial summarizes results from a comprehensive systematic review and meta-analysis, the largest to date, of all placebo-controlled randomized clinical trials (RCTs) on the effect of testosterone therapy on cardiovascular-related problems.

Last updated: 2018
L.ZA.MKT.GM.10.2016.1381